Article In Press | Published on: April 27, 2026
Volume: 2, Issue: 1
1. MVZ Labor Limbach und Kollegen, Heidelberg Im Breitspiel 1669126 Heidelberg, Germany.
DOI: null
Corresponding Author: Herbert Hof, MVZ Labor Limbach und Kollegen, Heidelberg Im Breitspiel 1669126 Heidelberg, Germany.
Citation: Hof H, Hofmann S. (2026). Which antibiotics are active against Lactobacillus iners playing the prominent role in the female urobiome? Journal of Infectious Diseases and Therapeutic Research. RPC Publishers. 2(1), 1-3.
Copyright: © 2026 Herbert Hof, this is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Urine is not sterile! Lactobacillus inners are the dominant agent in the human urobiome at least in women. These innocent bacteria attached firmly to the epithelium of the urinary bladder by strong interaction with the fibronectin on the surface of these cells. These colonizers inhibit uropathogenic bacteria to bind thus preventing the first step of an infection. Antibiotic therapy can interfere with the resident, protective flora. While ampicillin, pivmecillinam, cefotaxime,levofloxacin, nitroxoline and nitrofurantoin are active against L. iners. cotrimoxazole and fosfomycin are inactive.
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