Ulcer Preventive Properties of Boerhaavia Diffusa on Acetyl Salicylic Acid/Pylorus Ligated Ulcer Model in Rats

Article In Press | Published on: October 10, 2026

Volume: 2, Issue: 1

Authors: 1* Sharanabasappa A. Patil , 2 Somanath G. Patil

1. Reproductive Endocrinology Laboratory, Department of Zoology, Gulbarga University Kalaburagi - 585106, Karnataka, India.

2. Pharmaceutical Chemistry Division, Department of Chemistry, Gulbarga University Kalaburagi - 585106 Karnataka, India.


Corresponding Author: Sharanabasappa A. Patil, Reproductive Endocrinology Laboratory, Department of Zoology, Gulbarga University Kalaburagi - 585106, Karnataka, India.

Citation: Sharanabasappa A. Patil, Somanath G. Patil. (2026). Ulcer Preventive Properties of Boerhaavia Diffusa on Acetyl Salicylic Acid/Pylorus Ligated Ulcer Model in Rats. Journal of Surgical Case Reports and Research, RPC Publishers, 2(2); DOI: 10.66609/JSCRR-rpc.26.00565.

Copyright: © 2026 Sharanabasappa A. Patil, this is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Submitted On
June 23, 2026
Accepted On
September 25, 2026
Published On
October 10, 2026

Abstract

Ulcer protective activity of ethanol and water extract of Boerhaavia diffusa was studied in albino rats. The ethanol extract at two different doses of 400 and 800 mg/kg showed marked protection of the gastric mucosa on acetyl salicylic acid /pylorus ligated ulcer model. Whereas, the water extract was ineffective. Photochemical screening of ethanol and water extract has been carried out. The ulcer protective effect of ethanol extract may be due to increase in the gastric mucosa. Histological evidence supports the protection of gastric mucosa by the ethanol extract treatment.

Keywords

boerhaavia diffusa antiulcer gastroprotective pharmacology albino rat

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Keywords (categories)
Pharmacology